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Advancing
toward an objective assessment of pain
The
CHEPS (Contact Heat-Evoked Potential
Stimulator) is an advanced thermal
stimulator for pain evoked-potential
equipped with
functional MRI (fMRI) capabilities.
Used together with EEG recording
systems, CHEPS documents objective
response to pain perception by
investigating human thermal and
nociceptive pathways that mediate
sensory and pain perception. This is
achieved via selective stimulation and
identification of A-Delta & C-fibers
through EEG signal waveform recording.
SHEPS is considered the most advanced
and sophisticated device for pain
assessment available today, and is
opening and exciting opportunities in
pain research. Documenting and measuring
objective response to evoked-pain is
important in clinical and research
applications, such as assessing pain
associated with medications and
treatments. |
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Useful in monitoring, treating
and testing in:
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Useful in monitoring, treating
and testing in:
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fMRI
applications with long and
strong sensation evoked to
increase activation of brain
regions responsible for A-Delta
or C-Fibers
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Potential new "surrogate marker"
to prioritize new and existing
compounds to reduce
time-to-market in
pharmaceutical developmen
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Various phases of Clinical
trials for new drug development
- from basic level 'proof of
concept' to full Phase III
studies. |
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Through rapid and precise thermal
stimulation oscillation control, PATHWAY
(CHEPS Model) enables the evaluation of
temporal summation / Windup, providing
unique information regarding central
pain processing mechanisms related to
central sensitization. |
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Technological breakthrough
The CHEPS system deploys an extremely
rapid heating rate of 70°C/sec, to
deliver pain stimuli from baseline to
55°C in less than 250 milliseconds. This
rapid heating is possible due to Medoc’s
new 27mm diameter thermode and thermal
stimulator that enable testing large
skin areas to reach greater receptor
fields. The CHEPS system is equipped
with newly developed heat-foil
technology, combined with solid-state
thermoelectric cooler (Peltier
elements), as well as powerful
temperature controlled algorithms |
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CHEPS
Features
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Specially developed software enabling
test signals to be delivered online,
recorded (via EEG), saved and exported
for further data analysis
• Built with sophisticated hardware and
software for better temperature control,
ease of use and powerful performance
• Specific fast oscillation protocols
for windup
• Unique protocols for selective
stimulation of A-Delta & C fibers
• fMRI-compatibility (optional)
• Cold Sensation EP
• Full synchronization at stimuli start,
end and /or peak temperature, with EEG
or MRI (via TTL output)
• Flexible control of protocol
parameters (baseline, peak temp,
peak-to-peak intervals, warning signal)
• Versatile WINDOWS™ based software with
flexible selection range of test
paradigms for clinical, research and
drug trial requirements. Software meets
hospital requirements for maximum data
security and remote access for online
service
• Quick setup and system initialization
• Modular design for easy upgrade
• Mobile |
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Click here to
download EP application sheet
Click here to
download Pathway brochure |
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+ 55 11 3662-0752 -
+ 55 11 3825-7311 -
