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PATHWAY - Pain & Sensory Evaluation System

PATHWAY - A Configurable and Expandable Advanced Thermal Stimulator for today’s & tomorrow’s research protocols, pharmacologic investigations and clinical applications.

Contact-Heat Evoked Potential Stimulation (CHEPS)
PATHWAY enables pain and non-painful evoked potential recording of both A-delta & C-fiber function; allowing for the first time, selective activation & objective identification of nerve fiber activity through EEG recording. Extremely fast heating (70°C/Sec) and temperature sampling (150 times/second) delivers thermal stimuli from a baseline to 55°C in 250 milliseconds with precise temperature and pattern control.

	A Sequence of Fast Baseline-to-Peak Stimuli
	CHEPS generated EP Recordings

Windup
Superior temperature control capabilities for rapid and programmable delivery of sensory stimuli at a windup frequency (<0.33 Hz) in producing temporal pain summation.

"... an important modality for functional evaluation of central pain processing mechanisms related to central sensitizatio"

Advanced Thermal Stimulator (ATS)
ATS enables QST (Quantitative Sensory Testing) via delivery of painful and non-painful thermal stimuli. ATS thermal stimulation can range from -10°C to 54°C, thus opening new research horizons for deep cold pain & heat pain studies.

fMRI
PATHWAY is available in an fMRI compatible configuration in both ATS and CHEPS models. Rapid CHEPS stimulation can provide synchronized brain image & fMRI compatible EEG recording of A-delta & C-fiber electrophysiology.

Software Development Kit (SDK)
PATHWAY offers the option of a specially designed S/W program which can be integrated with popular research programs such as "LabView" and "MatLab", for controlling stimulation protocols.

Pharmaceutical Trials
PATHWAY can potentially be used as a new 'surrogate marker' assisting in prioritization of new & existing compounds, reduction of statistical sample, dosage definitions - all resulting in shortening time to market.

* Pending 510(k) clearance for the availability of the ATS Thermode in the USA for the use to 0°C degrees. The ATS Thermode is available Internationally for use to -10°C

For the PATHWAY brochure – click here

For the PATHWAY System Overview – click here