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PATHWAY - A Configurable and Expandable
Advanced Thermal Stimulator for today’s & tomorrow’s
research protocols, pharmacologic investigations and clinical
applications.
Contact-Heat Evoked Potential
Stimulation (CHEPS)
PATHWAY enables pain and non-painful evoked potential recording of
both A-delta & C-fiber function; allowing for the first time,
selective activation & objective identification of nerve fiber
activity through EEG recording. Extremely fast heating (70°C/Sec)
and temperature sampling (150 times/second) delivers thermal
stimuli from a baseline to 55°C in 250 milliseconds with precise
temperature and pattern control. |
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Windup
Superior temperature control capabilities for rapid and
programmable delivery of sensory stimuli at a windup frequency
(<0.33 Hz) in producing temporal pain summation.
"... an important modality for
functional evaluation of central pain processing mechanisms
related to central sensitizatio"
Advanced Thermal Stimulator
(ATS)
ATS enables QST (Quantitative Sensory Testing) via delivery of
painful and non-painful thermal stimuli. ATS thermal stimulation
can range from -10°C to 54°C, thus opening new research horizons
for deep cold pain & heat pain studies.
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Windup Protocol
Click the image
for large review |
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fMRI
PATHWAY is available in an fMRI compatible configuration in both
ATS and CHEPS models. Rapid CHEPS stimulation can provide
synchronized brain image & fMRI compatible EEG recording of
A-delta & C-fiber electrophysiology.
Software Development Kit (SDK)
PATHWAY offers the option of a specially designed S/W program
which can be integrated with popular research programs such as
"LabView" and "MatLab", for controlling
stimulation protocols.
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Ramp & Hold
Click the image for large review
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Pharmaceutical Trials
PATHWAY can potentially be used as a new 'surrogate marker'
assisting in prioritization of new & existing compounds,
reduction of statistical sample, dosage definitions - all
resulting in shortening time to market.
* Pending 510(k) clearance for the availability of the ATS
Thermode in the USA for the use to 0°C degrees. The ATS Thermode
is available Internationally for use to -10°C |
For the PATHWAY brochure – click
here
For the PATHWAY System Overview
– click
here |
+ 55 11 3662-0762
+ 55 11 3825-7311
